Description
Overview
Reversibly blocks the aromatase enzyme, lowering conversion of androgens to estradiol.
Composition / Profile
- Active compound: Anastrozole
- Drug class: Aromatase inhibitor (non-steroidal, reversible)
- Pack / dose (this listing): 25tab / 1mg
Format
- Oral tablet
- Pack / dose: 25tab / 1mg
Dosage & Usage Patterns
- Bodybuilding (commonly cited): Commonly cited on-cycle: ~0.25–0.5 mg EOD to 0.5 mg/day when managing aromatizing steroids; dose titrated to estradiol symptoms/bloodwork.
- Clinical / general reference: Very individual; over-suppressing estrogen is a common error and is itself harmful.
- Half-life: ~48 h.
- Protocols vary by individual, compound stack, and bloodwork — figures above reflect community-reported patterns, not medical recommendations.
Effects
Reported benefits (commonly cited)
- Lowers estradiol conversion from aromatizing androgens.
- Reduces water retention and gynecomastia risk.
- Helps manage estrogenic sides on cycle.
Reported side effects
- Joint pain, low-estrogen symptoms (low libido, mood, lethargy), negative effect on lipids and bone if estrogen is crushed.
Key Interactions
- Lowers estradiol.
- Interacts with anything estrogen-dependent.
- Affects bone/lipids.
Role in Post-Cycle Therapy
- Used on-cycle to manage aromatization, not a post-cycle recovery agent by itself.
Precautions
- Crashing estradiol causes real harm.
- Dosing should be guided by symptoms/bloodwork under a clinician.
Common Misconception
Myth: ‘more AI = better/drier.’
Evidence: excessively low estradiol harms joints, lipids, bone and libido.
Related Categories
- Browse more in Post Cycle Therapy (PCT) → Anastrozole.
Storage
- Store in a cool, dry place away from direct light and moisture






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